Advanced Super-Resolution Microscopy Systems for Precision Imaging

MICROSCOPY AND IMAGING delivers next-generation super-resolution systems that surpass diffraction limits for nanoscale imaging across research and industry.

Nanoscale Imaging with Advanced SRM Technologies

Super-Resolution Microscopy (SRM) overcomes the physical limits of conventional light microscopy by enabling nanoscale imaging at resolutions below 200 nanometers. Techniques such as STED, PALM, STORM, and SIM allow researchers to visualize subcellular structures, protein interactions, and nanoscale materials with unprecedented clarity. These imaging systems have become indispensable in fields like molecular biology, neuroscience, and nanotechnology.

Across North America, organizations depend on Super-Resolution Microscopy for applications that demand exacting detail and analytical precision. MICROSCOPY AND IMAGING supports this demand by offering scalable SRM platforms designed to meet the needs of cutting-edge research labs and high-tech industries. As a growing B2B leader, we combine advanced engineering, continuous development, and customer-centric support to deliver integrated imaging solutions that evolve with your work. Our commitment to reliability and innovation ensures your team can capture, analyze, and share highly resolved imaging data with confidence.

Core Components

In addition to offering products and systems developed by our team and trusted partners for Super-Resolution Microscopy, we are proud to carry top-tier technologies from Global Advanced Operations Tek Inc. (GAO Tek Inc.) and Global Advanced Operations RFID Inc. (GAO RFID Inc.). These reliable, high-quality products and systems enhance our ability to deliver comprehensive technologies, integrations, and services you can trust. Where relevant, we have provided direct links to select products and systems from GAO Tek Inc. and GAO RFID Inc.

Hardware

  • High-precision sensors (optical, electrochemical, infrared)
    Optical & Imaging Sensors– for capturing ultra-fine structural and chemical detail at the microscopic level.
  • Embedded processors with AI chipsets
    Device Edge (Edge Computing)– for real-time AI processing and data reduction directly within the analyzer.
  • Modular housings for environmental protection
    Industrial & Asset Monitoring Sensors (IoT Sensors) – ensuring analyzer durability in lab or harsh conditions.
  • Data acquisition modules and built-in calibration features
    Temperature & Process Calibrators (Environmental Test Instruments) – providing integrated, traceable calibration support.
  • Wireless and Ethernet-enabled communication ports
    Ethernet Media Converters (Ethernet) – enabling fast, reliable data transfer from microscopes to analysis stations.

Software

  • Real-time control of laser scanning and emission filtering
  • Image reconstruction algorithms specific to SRM technique (e.g., PALM, STORM)
  • Drift correction, alignment, and deconvolution tools
  • Data visualization in 2D, 3D, and time-lapse formats
  • API access for custom analysis workflows and integration

Cloud Services

  • High-capacity cloud storage for large dataset archiving
  • Real-time remote monitoring and image processing
  • Automated pipeline integration with AI-based feature detection
  • Secure collaboration environments for multi-site teams

Key Features and Functionalities

  • Resolution down to 10–20 nanometers (depending on technique)
  • Multi-color and multi-modal imaging options
  • Live-cell imaging with minimal phototoxicity (SIM, Live-STED)
  • Time-lapse imaging at nanoscale resolution
  • Modular configurations for method switching (e.g., switch between SIM and STORM)
  • High-throughput capabilities with fast acquisition modes

Integrations

MICROSCOPY AND IMAGING’s Super-Resolution Microscopy platforms can integrate with:

    • Structured illumination and adaptive optics systems
    • AI-powered segmentation and quantification software
    • Digital pathology networks and LIMS
    • Robotic sample loaders for batch imaging
    • Custom lab automation systems and smart analysis tools

Compatibility

  • Interfaces with microscope platforms from Nikon, Zeiss, Olympus, and Leica
  • Compatible with USB 3.0, FireWire, and Ethernet-based control systems
  • Supports third-party plugins and APIs (e.g., FIJI/ImageJ, CellProfiler, Python)
  • Cross-platform operation (Windows/macOS/Linux)
  • Integrates with cloud-based analytics and storage systems

Benefits

  • Achieve nanoscale resolution beyond diffraction limits
  • Analyze spatial protein organization and molecular architecture
  • Improve reproducibility with stable, automated workflows
  • Expand imaging capabilities with modular configurations
  • Enhance collaboration through cloud-enabled data sharing

Applications

  • Subcellular protein tracking and co-localization studies
  • Molecular neuroscience and synaptic analysis
  • Cancer research and biomarker discovery
  • Nanoscale inspection of polymers and materials
  • Pharmaceutical discovery and compound screening
  • Live-cell tracking and membrane dynamics analysis

Industries

  • Biomedical Research & Genomics
  • Neuroscience & Behavioral Science
  • Pharmaceutical R&D
  • Materials Science & Nanotechnology
  • Academic Core Facilities
  • Advanced Diagnostics & Biotech

Relevant Industry Standards

ISO 15189

FDA 21 CFR Part 11

ANSI/AAMI ST98

CLIA (U.S. Lab Certification)

Health Canada MDL (Medical Device Licensing)

Case Studies

Neuroscience Institute, California

A West Coast research center leveraged MICROSCOPY AND IMAGING’s PALM/STORM platform to map nanoscale protein distributions in neurons. With custom automation and analysis tools, the lab reduced imaging time per experiment by 35% and generated high-impact data for publication in peer-reviewed journals.

Pharmaceutical Company, Pennsylvania

A biopharma company implemented our STED-based super-resolution system for high-precision drug-target validation. The resulting data improved compound screening efficiency and helped the team shorten their lead optimization cycle by several weeks.

Nanomaterials Lab, Toronto

A nanotech research lab integrated MICROSCOPY AND IMAGING’s SIM-based super-resolution setup to investigate polymer self-assembly at the nanoscale. By coupling our system with cloud-based analytics, the team enhanced image throughput and facilitated remote collaboration across institutions.

Ready to elevate your imaging capabilities with super-resolution technology?

Get in touch with MICROSCOPY AND IMAGING for personalized recommendations, customized product solutions, and dedicated technical support. Let us help you harness the full potential of nanoscale visualization with systems tailored to your specific research or operational needs.

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